Open AccessBone-marrow mesenchymal stem cells reduce rat intestinal ischemia-reperfusion injury, ZO-1 downregulation and tight junction disruptionviaa TNF-α-regulated mechanism
Author(s) -
Zhongyang Shen,
Jing Zhang,
Hongli Song,
Weiping Zheng
Publication year - 2013
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v19.i23.3583
Subject(s) - downregulation and upregulation , tight junction , mesenchymal stem cell , tumor necrosis factor alpha , bone marrow , intestinal mucosa , pathology , medicine , stem cell , chemistry , biology , immunology , microbiology and biotechnology , biochemistry , gene
To investigate the effect of bone-marrow mesenchymal stem cells (BM MSCs) on the intestinal mucosa barrier in ischemia/reperfusion (I/R) injury.