Open AccessNotch2 regulates matrix metallopeptidase 9viaPI3K/AKT signaling in human gastric carcinoma cell MKN-45
Author(s) -
LingYun Guo,
Yumin Li,
Liang Qiao,
Tao Liu,
Yuanyuan Du,
Junqiang Zhang,
Wenting He,
Yiming Zhao,
Dong-Qiang He
Publication year - 2012
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v18.i48.7262
Subject(s) - pi3k/akt/mtor pathway , protein kinase b , hes1 , transfection , notch signaling pathway , gene silencing , biology , small interfering rna , cancer research , microbiology and biotechnology , cell growth , signal transduction , cell culture , gene , genetics , biochemistry
To clarify the role of activated Notch2 in the invasiveness of gastric cancer.