Open AccessEsophageal granular cell tumors: Report of 9 cases and a literature review
Author(s) -
Guofan Xu,
Hong-Tan Chen,
Cheng-Fu Xu,
Xiaodong Teng
Publication year - 2012
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v18.i47.7118
Subject(s) - medicine , esophagus , asymptomatic , granular cell , granular cell tumor , esophageal disease , endoscopic mucosal resection , endoscopic ultrasound , endoscopy , radiology , surgery , gastroenterology , immunohistochemistry , central nervous system
Esophageal granular cell tumors (GCTs) are rare tumors of the esophagus. We evaluated the clinical and pathologic features of 9 esophageal GCT patients (5 men and 4 women) from our institute and reviewed the related disease literature. Patient age ranged from 25 to 53 years (mean: 41 years). All the patients were asymptomatic or presented with non-specific symptoms. Most GCTs occurred in the distal esophagus and were less than 6 mm in diameter. Computational analysis showed that the average gray-scale endoscopic ultrasound images of esophageal GCTs were greater than that of esophageal leiomyomas. Eight patients were treated by endoscopic resection, and 1 patient underwent surgical excision. No post-therapy recurrence or metastasis developed during follow-up (mean: 36.4 mo, range: 1-72 mo).