Open AccessHeme oxygenase-1 prevents liver fibrosis in rats by regulating the expression of PPARγ and NF-κB
Author(s) -
Hui Yang,
Long Zhao,
Z. X. Zhao,
Yan Wang,
Jing Zhao,
Li Zhang
Publication year - 2012
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v18.i14.1680
Subject(s) - medicine , hydroxyproline , hemin , fibrosis , endocrinology , hepatic fibrosis , heme oxygenase , peroxisome proliferator activated receptor , liver injury , zinc protoporphyrin , chemistry , blot , receptor , heme , biochemistry , enzyme , gene
To investigate the effects of heme oxygenase (HO)-1 on liver fibrosis and the expression of peroxisome proliferator-activated receptor gamma (PPARγ) and nuclear factor-kappa B (NF-κB) in rats.