Open AccessNotch3 regulates the activation of hepatic stellate cells
Author(s) -
Yi-Xiong Chen,
Zhihong Weng,
Shuling Zhang
Publication year - 2012
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v18.i12.1397
Subject(s) - hepatic stellate cell , gene knockdown , blot , immunofluorescence , notch signaling pathway , immunohistochemistry , hes1 , hepatic fibrosis , pathology , transfection , signal transduction , transforming growth factor , biology , microbiology and biotechnology , fibrosis , cell culture , immunology , medicine , antibody , gene , biochemistry , genetics
To investigate whether Notch signaling is involved in liver fibrosis by regulating the activation of hepatic stellate cells (HSCs).