Open AccessLegalon-SIL downregulates HCV core and NS5A in human hepatocytes expressing full-length HCV
Author(s) -
Marjan Mehrab-Mohseni,
Hossein Sendi,
Nury Steuerwald,
Sriparna Ghosh,
Laura W. Schrum,
Herbert L. Bonkovsky
Publication year - 2011
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v17.i13.1694
Subject(s) - ns5a , hepatitis c virus , microbiology and biotechnology , virology , rna , hepatitis c , blot , messenger rna , real time polymerase chain reaction , hepacivirus , biology , chemistry , gene , virus , biochemistry
To determine the effect of Legalon-SIL (LS) on hepatitis C virus (HCV) core and NS5A expression and on heme oxygenase-1 (HMOX-1) and its transcriptional regulators in human hepatoma cells expressing full length HCV genotype 1b.