Open AccessProtection of the liver against CCl4-induced injury by intramuscular electrotransfer of a kallistatin-encoding plasmid
Author(s) -
Yong Diao,
Xiaofeng Zhao,
Junsheng Lin,
Qizhao Wang,
Rong Xu
Publication year - 2011
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v17.i1.111
Subject(s) - ccl4 , liver injury , oxidative stress , carbon tetrachloride , chemistry , transgene , microbiology and biotechnology , tumor necrosis factor alpha , necrosis , pharmacology , immunology , medicine , biology , biochemistry , gene , organic chemistry
To investigate the effect of transgenic expression of kallistatin (Kal) on carbon tetrachloride (CCl(4))-induced liver injury by intramuscular (im) electrotransfer of a Kal-encoding plasmid formulated with poly-L-glutamate (PLG).