Open AccessBlocking effects of siRNA on VEGF expression in human colorectal cancer cells
Author(s) -
Yuan Yin,
Lei Cao,
Wenqing Wu,
Hao Li,
Yan Jiang,
Hongfu Zhang
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i9.1086
Subject(s) - small interfering rna , transfection , vascular endothelial growth factor , cell growth , microbiology and biotechnology , cancer research , immunocytochemistry , flow cytometry , biology , lipofectamine , vascular endothelial growth factor a , blot , cell culture , pathology , medicine , vegf receptors , recombinant dna , biochemistry , genetics , gene , vector (molecular biology)
To investigate the expression of vascular endothelial cell growth factor (VEGF) and its receptors Fms-like tyrosine kinase 1 (FLT-1) and fetal liver kinase 1 (FLK-1) in colorectal carcinoma (CRC), and the blocking effects of small interfering RNAs (siRNAs) on VEGF expression in human colorectal cancer HCT116 cells.