Open AccessUp-regulation of PIK3CA promotes metastasis in gastric carcinoma
Author(s) -
Jifang Liu,
Xinke Zhou,
Jinhui Chen,
Yi Gao,
He-Ge Chen,
Mingchen Ba,
Sheng-Qu Lin,
Yanfei Qi
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i39.4986
Subject(s) - protein kinase b , pi3k/akt/mtor pathway , metastasis , immunohistochemistry , cancer research , cancer , downregulation and upregulation , medicine , pathology , signal transduction , biology , microbiology and biotechnology , gene , biochemistry
To explore expressions of PIK3CA in the progression of gastric cancer from primary to metastasis and its effects on activation of phosphatidylinositol 3-kinase (PI3K)/Akt pathway.