Open AccessHBx-induced reactive oxygen species activates hepatocellular carcinogenesisviadysregulation of PTEN/Akt pathway
Author(s) -
Hojin Ha
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i39.4932
Subject(s) - hbx , pten , protein kinase b , reactive oxygen species , tensin , carcinogenesis , cancer research , chemistry , pi3k/akt/mtor pathway , cell growth , microbiology and biotechnology , signal transduction , biology , biochemistry , transfection , gene
To investigate the role of hepatitis B virus X-protein (HBx)-induced reactive oxygen species (ROS) on liver carcinogenesis in HBx transgenic mice and HepG2-HBx cells.