Open AccessGermline mutation analysis ofhPMS2gene in Chinese families with hereditary nonpolyposis colorectal cancer
Author(s) -
Xia Sheng,
HuanXiang Zhou,
Xiao Zhou,
Du Xiang,
Tai Ming Zhang,
San Jun Cai,
Sheng Wei,
Da Shi
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i30.3847
Subject(s) - genetics , missense mutation , proband , exon , germline mutation , mutation , biology , single nucleotide polymorphism , gene , genotype
To study the germline mutation of hPMS2 gene in 26 unrelated Chinese hereditary nonpolyposis colorectal cancer (HNPCC) probands and to fulfill the screening strategy for HNPCC in Chinese.