Open AccessNon-peptidyl low molecular weight radical scavenger IAC attenuates DSS-induced colitis in rats
Author(s) -
Valentina Vasina,
Massimiliano Broccoli,
Maria Ursino,
Donatella Canistro,
Luca Valgimigli,
Antonio Soleti,
Moreno Paolini,
Fabrizio De Ponti
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i29.3642
Subject(s) - myeloperoxidase , colitis , chemistry , ulcerative colitis , inflammatory bowel disease , pharmacology , inflammation , glutathione , reactive oxygen species , infiltration (hvac) , immunology , biochemistry , medicine , enzyme , disease , physics , thermodynamics
To investigate the effects of the free radical scavenger bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)decandioate (IAC) in the dextran sodium sulphate (DSS) experimental model of ulcerative colitis.