Open AccessRoux-en-Y gastric bypass promotes expression of PDX-1 and regeneration of β-cells in Goto-Kakizaki rats
Author(s) -
Zhen Li,
Zhang Hong-ya,
Luxian Lv,
Dongfei Li,
Jingxing Dai,
Ou Sha,
Wenqiang Li,
Yu Bai,
Yuan Lin
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i18.2244
Subject(s) - neogenesis , immunohistochemistry , medicine , endocrinology , roux en y anastomosis , gastric bypass , reverse transcription polymerase chain reaction , messenger rna , insulin , chemistry , islet , obesity , weight loss , biochemistry , gene
To study the effects of Roux-en-Y gastric bypass (RYGB) on the expression of pancreatic duodenal homeobox-1 (PDX-1) and pancreatic beta-cell regeneration/neogenesis, and their possible mechanisms in diabetics.