Open AccessRefractory gastric ulcer with abundant IgG4-positive plasma cell infiltration: A case report
Author(s) -
Takayoshi Fujita,
Takafumi Ando,
Makoto Sakakibara,
Waki Hosoda,
Hidemi Goto
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i17.2183
Subject(s) - medicine , autoimmune pancreatitis , helicobacter pylori , infiltration (hvac) , refractory (planetary science) , gastroenterology , pathology , pancreatitis , biology , physics , astrobiology , thermodynamics
We describe a 77-year-old man with refractory gastric ulcer that worsened after Helicobacter pylori eradication therapy. Pathology showed marked infiltration of IgG4-positive plasma cells in the gastric lesions, which led us to suspect IgG4-related sclerosing disease. To the best of our knowledge, this is the first report of IgG4-related gastric ulcer without the main manifestation of autoimmune pancreatitis.