Open AccessMolecular determinants of the antitumor effects of trichostatin A in pancreatic cancer cells
Author(s) -
Elisabeth Emonds,
Brit Fitzner,
Robert Jaster
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i16.1970
Subject(s) - trichostatin a , chemistry , histone deacetylase inhibitor , cell culture , mapk/erk pathway , microbiology and biotechnology , protein kinase b , cancer research , kinase , p38 mitogen activated protein kinases , apoptosis , histone , biology , histone deacetylase , biochemistry , dna , genetics
To gain molecular insights into the action of the histone deacetylase inhibitor (HDACI) trichostatin-A (TSA) in pancreatic cancer (PC) cells.