Open AccessNatural epitope variants of the hepatitis C virus impair cytotoxic T lymphocyte activity
Author(s) -
Shuping Wang,
Rico Buchli,
Jonathan R. Schiller,
Jingtao Gao,
Rodney S. VanGundy,
William H. Hildebrand,
David D. Eckels
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i16.1953
Subject(s) - epitope , biology , virology , hepatitis c virus , ctl* , ns3 , major histocompatibility complex , microbiology and biotechnology , human leukocyte antigen , cytotoxic t cell , antigen , virus , cd8 , genetics , in vitro
To understand how interactions between hepatitis C virus (HCV) and the host's immune system might lead to viral persistence or effective elimination of HCV.