Open AccessMelatonin and Doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines
Author(s) -
Lulu Fan,
Guoping Sun,
Wei Wei,
Zhanggui Wang,
Ge Liu,
Wei-Zheng Fu,
Hua Wang
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i12.1473
Subject(s) - apoptosis , melatonin , flow cytometry , cell growth , viability assay , tunel assay , cell culture , microbiology and biotechnology , mtt assay , biology , cell , doxorubicin , chemistry , endocrinology , biochemistry , genetics , chemotherapy
To investigate whether melatonin has synergistic effects with doxorubicin in the growth-inhibition and apoptosis-induction of human hepatoma cell lines HepG2 and Bel-7402.