Open AccessLittoral-cell angioma of the spleen: A case report
Author(s) -
Ángel Cosme,
Ángel Tejada,
Luís Bujanda,
Manuel Vaquero,
José Luis Elorza,
E Ojeda,
Unai Goikoetxea
Publication year - 2007
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v13.i48.6603
Subject(s) - spleen , cd68 , medicine , red pulp , splenectomy , pathology , differential diagnosis , splenic disease , angioma , surgery , vascular disease , immunohistochemistry
Littoral-cell angioma (LCA) is a primary splenic vascular tumor that arises from the normal littoral cells lining the sinus channels of the splenic red pulp. We report a case of LCA of the spleen, which has been infrequently communicated in the literature. A 76-year-old man with a 2-wk history of weight loss, abdominal pain and changes in bowel habits was admitted to our hospital. Imaging studies (CT and MRI) showed multiple lesions in the spleen. Splenectomy was performed. Lining cells were positive for CD31/CD68 markers. Our case was associated with a serrated colonic adenoma. LCA is a benign vascular tumor of the spleen that needs to be included in the differential diagnosis of multiple splenic nodules.