Open AccessShRNA-mediated gene silencing of β-catenin inhibits growth of human colon cancer cells
Author(s) -
WenSheng Huang,
Jianping Wang,
Ting Wang,
Jieyu Fang,
Ping Lan,
Jingfei Ma
Publication year - 2007
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v13.i48.6581
Subject(s) - small hairpin rna , gene silencing , cell cycle , cell growth , transfection , wnt signaling pathway , microbiology and biotechnology , cancer research , apoptosis , biology , cell culture , chemistry , signal transduction , gene knockdown , gene , genetics
To observe the gene silencing mediated by the specific shRNA targeted against beta-catenin and its effect on cell proliferation and cycle distribution in the human colon cancer cell line Colo205.