Open AccessTwo distinct pathways of p16 gene inactivation in gallbladder cancer
Author(s) -
Hiroyuki Tadokoro
Publication year - 2007
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v13.i47.6396
Subject(s) - loss of heterozygosity , biology , dna methylation , methylation , cancer research , microbiology and biotechnology , gene , gallbladder cancer , promoter , cancer , immunohistochemistry , gene expression , genetics , allele , immunology
To examine the mechanism of inactivation of the p16 gene in gallbladder cancer, and to investigate p16 alterations and their correlation with clinicopathological features.