Open AccessTargeting hepatitis B virus antigens to dendritic cells by heat shock protein to improve DNA vaccine potency
Author(s) -
Qinxuan Gu,
Xue F. Huang,
Wenhong Ren,
Lei Shen,
Bing-ya Liu,
Si-Yi Chen
Publication year - 2007
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v13.i44.5911
Subject(s) - elispot , dna vaccination , ctl* , hbeag , virology , antigen , cytotoxic t cell , immune system , biology , hepatitis b virus , immunology , cd8 , immunization , hbsag , virus , in vitro , biochemistry
To investigate a novel DNA vaccination based upon expression of the HBV e antigen fused to a heat shock protein (HSP) as a strategy to enhance DNA vaccine potency.