Open AccessInhibition of histone deacetylase for the treatment of biliary tract cancer: A new effective pharmacological approach
Author(s) -
Thilo Bluethner,
Manuel Niederhagen,
Karel Caca,
F. Serr,
Helmut Witzigmann,
Christian Moebius,
Joachim Mössner,
Marcus Wiedmann
Publication year - 2007
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v13.i35.4761
Subject(s) - biology , gemcitabine , histone deacetylase , mtt assay , in vivo , apoptosis , cancer research , cell cycle , biliary tract , cell growth , gallbladder cancer , cancer , medicine , histone , biochemistry , gene , genetics , microbiology and biotechnology
To investigate in vitro and in vivo therapeutic effects of histone deacetylase inhibitors NVP-LAQ824 and NVP-LBH589 on biliary tract cancer.