Open AccessTherapeutic proteasome inhibition in experimental acute pancreatitis
Author(s) -
Tamás Letoha,
L Fehér,
László Pecze,
Csaba Somlai,
I Varga,
József Kaszaki,
Gábor Tóth,
Csaba Vízler,
László Tiszlavicz,
Tamás Takács
Publication year - 2007
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v13.i33.4452
Subject(s) - mg132 , proteasome inhibitor , acute pancreatitis , pancreatitis , proteasome , oxidative stress , inflammation , pharmacology , medicine , cholecystokinin , heat shock protein , chemistry , endocrinology , biochemistry , receptor , gene
To establish the therapeutic potential of proteasome inhibition, we examined the therapeutic effects of MG132 (Z-Leu-Leu-Leu-aldehyde) in an experimental model of acute pancreatitis.