Open AccessImportance of MutL homologue MLH1 and MutS homologue MSH2 expression in Turkish patients with sporadic colorectal cancer
Author(s) -
Sibel Erdamar,
Esra Ucaryilmaz,
Gökhan Demir,
Tayfun Karahasanoğlu,
Gülen Doğusoy,
Ahmet Dirican,
Süha Göksel
Publication year - 2007
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v13.i33.4437
Subject(s) - msh2 , mlh1 , microsatellite instability , colorectal cancer , immunohistochemistry , cancer research , msh6 , dna mismatch repair , biology , tissue microarray , pathology , cancer , medicine , genetics , gene , microsatellite , allele
To assess the incidence of MLH1 (the human MutL homologue) and MSH2 (the human MutS homologue) protein expression in Turkish patients with sporadic colorectal cancers and to compare their survival and clinicopathological features.