Open AccessApoptotic effect of Epigallocatechin-3-gallate on the human gastric cancer cell line MKN45viaactivation of the mitochondrial pathway
Author(s) -
Zhihua Ran,
Qi Xu,
Jinlu Tong,
Shu–Dong Xiao
Publication year - 2007
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v13.i31.4255
Subject(s) - apoptosis , annexin , downregulation and upregulation , western blot , cell culture , gallate , microbiology and biotechnology , caspase 3 , cancer cell , mitochondrion , pi , caspase , caspase 9 , chemistry , epigallocatechin gallate , inner mitochondrial membrane , biology , cancer , programmed cell death , biochemistry , pharmacology , polyphenol , gene , antioxidant , genetics
To investigate whether Epigallocatechin-3-gallate (EGCG) can induce apoptosis of the gastric cancer cell line MKN45 and its apoptotic pathway.