Open AccessNAT2*6A, a haplotype of the N-acetyltransferase 2 gene, is an important biomarker for risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis
Author(s) -
Norihide Higuchi,
Naoko Tahara,
Katsunori Yanagihara,
Kiyoyasu Fukushima,
Naofumi Suyama,
Yuichi Inoue,
Yoshitsugu Miyazaki,
Tsutomu Kobayashi,
Koh-ichiro Yoshiura,
Norio Niikawa,
Chun-Yang Wen,
Hajime Isomoto,
Saburo Shikuwa,
Katsuhisa Omagari,
Yohei Mizuta,
Shigeru Kohno,
Kazuhiro Tsukamoto
Publication year - 2007
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v13.45.6003
Subject(s) - haplotype , medicine , tuberculosis , odds ratio , genotype , gastroenterology , single nucleotide polymorphism , immunology , biology , pathology , gene , genetics
To investigate an association between N-acetyltransferase 2 (NAT2)-haplotypes/diplotypes and adverse effects in Japanese pulmonary tuberculosis patients.