Open AccessInterleukin-1 beta up-regulates tissue inhibitor of matrix metalloproteinase-1 mRNA and phosphorylation of c-jun N-terminal kinase and p38 in hepatic stellate cells
Author(s) -
Yaping Zhang,
X.X. Yao,
Xiuhe Zhao
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i9.1392
Subject(s) - hepatic stellate cell , p38 mitogen activated protein kinases , phosphorylation , messenger rna , western blot , matrix metalloproteinase , kinase , microbiology and biotechnology , chemistry , biology , medicine , andrology , endocrinology , protein kinase a , biochemistry , gene
To study the relationship between interleukin-1beta (IL-1beta) up-regulating tissue inhibitor of matrix metalloproteinase-1 (TIMMP-1) mRNA expression and phosphorylation of both c-jun N-terminal kinase (JNK) and p38 in rat hepatic stellate cells (HSC).