Open AccessMicrobubble-enhanced ultrasound exposure improves gene transfer in vascular endothelial cells
Author(s) -
Fang Nie,
Hui-Xiong Xu,
Qing Tang,
Ming-De Lu
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i46.7508
Subject(s) - fluorescein isothiocyanate , transfection , umbilical vein , ultrasound , flow cytometry , microbiology and biotechnology , medicine , genetic enhancement , membrane permeability , gene delivery , andrology , pathology , chemistry , immunology , in vitro , gene , biology , membrane , fluorescence , biochemistry , radiology , physics , quantum mechanics
To explore the effects of ultrasound exposure combined with microbubble contrast agent (SonoVue) on the permeability of the cellular membrane and on the expression of plasmid DNA encoding enhanced green fluorescent protein (pEGFP) transfer into human umbilical vein endothelial cells (HUVECs).