Open AccessN-terminal and C-terminal cytosine deaminase domain of APOBEC3G inhibit hepatitis B virus replication
Author(s) -
Yizhu Lei,
Yongjun Tian,
Haiyan Ding,
Baoju Wang,
Yan Yang,
Yixue Hao,
Xingwei Zhao,
Mengji Lu,
Fei-Li Gong,
Dongliang Yang
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i46.7488
Subject(s) - hepatitis b virus , virology , microbiology and biotechnology , biology , hbcag , hbsag , cytosine deaminase , virus , biochemistry , gene , genetic enhancement
To investigate the effect of human apolipoprotein B mRNA-editing enzyme catalytic-polypeptide 3G (APOBEC3G) and its N-terminal or C-terminal cytosine deaminase domain-mediated antiviral activity against hepatitis B virus (HBV) in vitro and in vivo.