Down-regulation of Bcl-XLby RNA interference suppresses cell growth and induces apoptosis in human esophageal cancer cells | Zendy

Yong-En Xie | Zendy

Open Access

Down-regulation of Bcl-X_Lby RNA interference suppresses cell growth and induces apoptosis in human esophageal cancer cells

Author(s) -

Yong-En Xie

Publication year - 2006

Publication title -

world journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 155

eISSN - 2219-2840

pISSN - 1007-9327

DOI - 10.3748/wjg.v12.i46.7472

Subject(s) - small interfering rna , transfection , lipofectamine , apoptosis , rna interference , esophageal cancer , microbiology and biotechnology , cancer cell , biology , cell , cancer research , cell growth , vector (molecular biology) , expression vector , cancer , cell culture , rna , gene , biochemistry , genetics , recombinant dna

To determine the inhibitory effect of the vector-generated small interfering RNAs (siRNAs) on the expression of the Bcl-X(L) gene in established human esophageal cancer cells, and to investigate the effect of the Bcl-X(L) siRNAs on cell growth and apoptosis in esophageal cancer cells.

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