Open AccessEffects of IκBα and its mutants on NF-κB and p53 signaling pathways
Author(s) -
Xian Li,
Da Xing,
Ju Wang,
Debin Zhu,
Lan Zhang,
Xiaojia Chen,
Fenyong Sun,
An Hong
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i41.6658
Subject(s) - transfection , microbiology and biotechnology , mutant , cytoplasm , biology , gene , biochemistry
To study the effects of IkappaBalpha and its mutants (IkappaBalphaM, IkappaBalpha243N, IkappaBalphaM244C) on NF-kappaB, p53 and their downstream target genes. The relationship of NF-kappaB, p53, and IkappaBalpha was further discussed.