Open AccessSeverity of ulcerative colitis is associated with a polymorphism at diamine oxidase gene but not at histamine N-methyltransferase gene
Author(s) -
Elena GarcíaMartín,
Juan L. Mendoza,
Carmen Martı́nez,
Carlos Taxonera,
Elena Urcelay,
José M. Ladero,
Emilio G. de la Concha,
Manuel DíazRubio,
José A.G. Agúndez
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i4.615
Subject(s) - diamine oxidase , histamine n methyltransferase , allele , ulcerative colitis , histamine , genotype , allele frequency , gastroenterology , immunology , medicine , gene , biology , enzyme , genetics , biochemistry , disease , histamine h2 receptor , receptor , antagonist
To analyse the role of two common polymorphisms in genes coding for histamine metabolising enzymes as it relates to the risk to develop ulcerative colitis (UC) and the clinical course of these patients.