Open AccessAttenuation of gastric mucosal inflammation induced by aspirin through activation of A2Aadenosine receptor in rats
Author(s) -
Masaru Odashima
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i4.568
Subject(s) - aspirin , agonist , gastric mucosa , myeloperoxidase , medicine , ulcer index , adenosine , proinflammatory cytokine , pharmacology , inflammation , stomach , receptor , chemistry , endocrinology
To determine whether a specific adenosine A(2A) receptor agonist (ATL-146e) can ameliorate aspirin-induced gastric mucosal lesions in rats, and reduce neutrophil accumulation and production of pro-inflammatory cytokines.
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