Open AccessHepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells
Author(s) -
Raquel TalénsVisconti,
Ana Bonora,
Ramiro Jover,
Vicente Mirabet,
F Carbonell,
José V. Castell,
Marı́a José Gómez-Lechón
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i36.5834
Subject(s) - stem cell , mesenchymal stem cell , adipose tissue , transdifferentiation , stem cell transplantation for articular cartilage repair , amniotic stem cells , adult stem cell , biology , bone marrow , cellular differentiation , stem cell marker , clinical uses of mesenchymal stem cells , pathology , microbiology and biotechnology , immunology , endocrinology , medicine , biochemistry , gene
To investigate and compare the hepatogenic transdifferentiation of adipose tissue-derived stem cells (ADSC) and bone marrow-derived mesenchymal stem cells (BMSC) in vitro. Transdifferentiation of BMSC into hepatic cells in vivo has been described. Adipose tissue represents an accessible source of ADSC, with similar characteristics to BMSC.