Open AccessDetection of YMDD mutation using mutant-specific primers in chronic hepatitis B patients before and after lamivudine treatment
Author(s) -
Cha-Ze Lee,
Hsuan-Shu Lee,
GuanTarn Huang,
PeiMing Yang,
JinChuan Sheu
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i33.5301
Subject(s) - lamivudine , mutant , primer (cosmetics) , hbeag , virology , microbiology and biotechnology , wild type , hbsag , biology , hepatitis b virus , chemistry , virus , genetics , gene , organic chemistry
To develop a PCR assay using mutant-specific primers to detect mutation of tyrosine-methionine-aspartate-aspartate (YMDD) motif of HBV to tyrosine-valine-aspartate-aspartate (YVDD) or tyrosine-isoleucine-aspartate-aspartate (YIDD).