Open AccessIntestinal permeability of metformin using single-pass intestinal perfusion in rats
Author(s) -
Ning Song,
Quansheng Li,
Changxiao Liu
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i25.4064
Subject(s) - metformin , jejunum , duodenum , ileum , verapamil , intestinal permeability , medicine , small intestine , chemistry , endocrinology , pharmacology , gastroenterology , calcium , insulin
To characterize the intestinal transport and mechanism of metformin in rats and to investigate whether or not metformin is a substrate for P-glycoprotein (P-gp).