Open AccessEffect of blocking IGF-I receptor on growth of human hepatocellular carcinoma cells
Author(s) -
Youcheng Zhang,
Xiaopeng Wang,
Lingyi Zhang,
Ailin Song,
Zhi-Min Kou,
Xusheng Liu
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i25.3977
Subject(s) - flow cytometry , apoptosis , cell culture , cell growth , hepatocellular carcinoma , microbiology and biotechnology , monoclonal antibody , receptor , cell cycle , biology , endocrinology , chemistry , medicine , andrology , antibody , cancer research , immunology , biochemistry , genetics
To study the expression level and localization of insulin-like growth factor -I receptor (IGF-IR) in HepG2 cells and Chang liver cells, and to observe the effect of anti-IGF-IR monoclonal antibody (alphaIR3) on the growth of HepG2 cells.