Open AccessHigh efficient mammalian expression and secretion of a functional humanized single-chain Fv/human interleukin-2 molecules
Author(s) -
Yao Shên,
Xuehao Wang,
Xiaoming Wang,
Zao-Lai Chen,
Xiping Shen,
Chaochen Zhao,
Jun Li
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i24.3859
Subject(s) - fusion protein , immunogenicity , recombinant dna , microbiology and biotechnology , transfection , humanized antibody , antibody , monoclonal antibody , biology , cell culture , chemistry , biochemistry , immunology , gene , genetics
To construct and produce a recombinant bispecific humanized single-chain Fv (sFv) /Interleukin-2 (IL-2) fusion protein by using mammalian cells.