Open AccessIncreased hepatic expression of insulin-like growth factor-I receptor in chronic hepatitis C
Author(s) -
José Tadeu Stefano,
Maria Lúcia Corrêa-Giannella,
C. M. F. Ribeiro,
Venâncio Avancini Ferreira Alves,
Paulo Celso Bosco Massarollo,
Marcel Cerqueira César Machado,
Daniel Giannella-Neto
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i24.3821
Subject(s) - hepatocellular carcinoma , cirrhosis , insulin like growth factor , medicine , endocrinology , hepatitis c virus , hepatocyte , hepatology , growth factor , hepatitis c , ribavirin , messenger rna , liver transplantation , gene expression , immunohistochemistry , liver regeneration , biology , receptor , transplantation , immunology , virus , regeneration (biology) , gene , biochemistry , in vitro , microbiology and biotechnology
Although increased insulin-like growth factor-I receptor (IGF-IR) gene expression has been reported in hepatocellular carcinoma, studies assessing IGF-IR in chronic hepatitis C (CHC) and cirrhosis are scarce. We therefore aimed to evaluate IGF-IR and IGF-I mRNA expression in liver from patient with CHC.