Open AccessExpression of Interleukin-11 and Interleukin-11 receptor α in human colorectal adenocarcinoma; Immunohistochemical analyses and correlation with clinicopathological factors
Author(s) -
Kazuyuki Yamazumi,
Toshiyuki Nakayama,
Takafumi Kusaba,
Chun Yang Wen,
Ayumi Yoshizaki,
Yuichi Yakata,
Takeshi Nagayasu,
Ichiro Sekine
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i2.317
Subject(s) - immunohistochemistry , adenocarcinoma , lymphovascular invasion , pathology , colorectal cancer , metastasis , biology , cancer , medicine , cancer research
There is strong evidence that interleukin-11 (IL-11) is involved in the regulation of tumor progression, cellular growth and differentiation. Recently, interleukin-11 receptor (IL-11R) has been detected on some cancer cells. In this study, we investigated the expression of IL-11 and IL-11R in colorectal adenocarcinoma.