Open AccessAnticancer and cytotoxic properties of the latex of Calotropis procera in a transgenic mouse model of hepatocellular carcinoma
Author(s) -
Tenzin Choedon,
Mathan Ganeshan,
Soneera Arya,
Vijay Kumar,
Vijay Kumar
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i16.2517
Subject(s) - dna fragmentation , apoptosis , cytotoxicity , cytotoxic t cell , chemistry , fragmentation (computing) , cell culture , calotropis procera , programmed cell death , pharmacology , toxicity , mtt assay , hepatocellular carcinoma , microbiology and biotechnology , biochemistry , biology , in vitro , traditional medicine , medicine , cancer research , ecology , genetics , organic chemistry
To evaluate the anticancer property of the dried latex (DL) of Calotropis procera, a tropical medicinal plant, in the X15-myc transgenic mouse model of hepatocellular carcinoma and to elucidate its mechanism of action in cell culture.