Open AccessEffect of NaCl and Helicobacter pylori vacuolating cytotoxin on cytokine expression and viability
Author(s) -
Juan Sun
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i14.2174
Subject(s) - viability assay , cytokine , helicobacter pylori , microbiology and biotechnology , tumor necrosis factor alpha , vacuole , interleukin 8 , gastric mucosa , chemistry , staining , biology , cell , immunology , stomach , cytoplasm , biochemistry , genetics
To determine whether Helicobacter pylori (H pylori) vacuolating cytotoxin (VacA) regulates release of pro-inflammatory cytokines (IL-1beta, IL-8, TNF-alpha, and IL-6) or alters gastric epithelial cell viability and to determine whether NaCl affects these VacA-induced changes.