Open AccessMechanisms inactivating the gene for E-cadherin in sporadic gastric carcinomas
Author(s) -
Yao–Chi Liu,
ChenYang Shen,
HurngSheng Wu,
TsaiYuan Hsieh,
De-Chuan Chan,
ChengJueng Chen,
JyhCherng Yu,
ChengPing Yu,
HorngJyh Harn,
PengJen Chen,
Chung-Bao Hsieh,
Teng-Wei Chen,
Huan-Mieng Hsu
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i14.2168
Subject(s) - cdh1 , loss of heterozygosity , biology , dna methylation , microbiology and biotechnology , cadherin , methylation , cancer research , gene , allele , genetics , gene expression , cell
To study the role of CDH1/E-cadherin (E-cad) gene alteration profiles including mutation, loss of heterozygosity (LOH), promoter polymorphism and hypermethylation in mechanisms of CDH1 inactivation in gastric carcinoma (GC).