Open AccessRosuvastatin reduces rat intestinal ischemia-reperfusion injury associated with the preservation of endothelial nitric oxide synthase protein
Author(s) -
Yuji Naito,
Kazuhiro Katada,
Tomohisa Takagi,
Hisato Tsuboi,
Masaaki Kuroda,
Osamu Handa,
Satoshi Kokura,
Norimasa Yoshida,
Hiroshi Ichikawa,
Toshikazu Yoshikawa
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i13.2024
Subject(s) - rosuvastatin , nitric oxide synthase , enos , reperfusion injury , inflammation , endocrinology , medicine , nitric oxide , intestinal mucosa , myeloperoxidase , ischemia , pharmacology , chemistry
To investigate the protective effect of rosuvastatin on ischemia-reperfusion (I-R)-induced small intestinal injury and inflammation in rats, and to determine the effect of this agent on the expression of endothelial nitric oxide synthase (eNOS) protein.