Open AccessJumbo biopsy is useful for the diagnosis of colonic prolapsing mucosal polyps with diverticulosis
Author(s) -
Shingo Kato,
Kazutoshi Hashiguchi,
Ryōichi Yamamoto,
Mitsuru Seo,
Takashi Mizutani,
Kazuro Itoh,
Akinori Iwashita,
Soichiro Miura
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i10.1634
Subject(s) - medicine , lamina propria , biopsy , colonoscopy , diverticulosis , sigmoid colon , pathology , gastroenterology , barium enema , rectum , epithelium , colorectal cancer , cancer
We report here a case of multiple prolapsing mucosal polyps with diverticulosis in the sigmoid colon. A 52-year-old man was admitted to our hospital because of bloody diarrhea. Colonoscopy and barium enema showed multiple diverticula, markedly thickened mucosal folds and polypoid lesions with mucus on the top of them in the sigmoid colon. Endoscopic ultrasonography showed thickening of the mucosal and submucosal layers. Several endoscopic biopsy specimens were taken from the polypoid lesions. Histological examination revealed only chronic inflammatory cell infiltration. In order to obtain a definite diagnosis, we performed endoscopic jumbo biopsy for the polypoid lesions after obtaining informed consent. Histological examination revealed marked lymphocyte infiltration, hemosiderin deposits and fibromuscular obliteration in the lamina propria, features similar to those of mucosal prolapsing syndrome. After anti-diarrhetic treatment, clinical findings were improved. Thus, jumbo biopsy is useful for diagnosis and treatment of prolapsing mucosal polyps.