Open AccessAntithrombin reduces reperfusion-induced hepatic metastasis of colon cancer cells
Author(s) -
Masahiro Kurata,
Kenji Okajima,
Toru Kawamoto,
Mitsuhiro Uchiba,
Nobuhiro Ohkohchi
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i1.60
Subject(s) - argatroban , metastasis , medicine , tumor necrosis factor alpha , antithrombin , endocrinology , cancer , chemistry , pathology , thrombin , platelet , heparin
To examine whether antithrombin (AT) could prevent hepatic ischemia/reperfusion (I/R)-induced hepatic metastasis by inhibiting tumor necrosis factor (TNF)-alpha-induced expression of E-selectin in rats.