Open AccessInhibitory effect of Polo-like kinase 1 depletion on mitosis and apoptosis of gastric cancer cells
Author(s) -
Xuehua Chen,
Bin Lan,
Ying Qu,
Xiaoqing Zhang,
Qing Cai,
Bingya Liu,
Zhenggang Zhu
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i1.29
Subject(s) - polo like kinase , plk1 , mitosis , cyclin dependent kinase 1 , cyclin b1 , cancer research , biology , cytokinesis , cell cycle , cancer cell , cyclin b , microbiology and biotechnology , apoptosis , cancer , cyclin , cell , cell division , biochemistry , genetics
Polo-like kinase 1 (PLK1) serine/threonine kinase plays a vital role in multiple phases of mitosis in gastric cancer cells. To investigate the effect of PLK1 depletion on mitosis and apoptosis of gastric cancer cells.