Open AccessActivation of STAT3 signaling in human stomach adenocarcinoma drug-resistant cell line and its relationship with expression of vascular endothelial growth factor
Author(s) -
Li Yu,
Ying Cheng,
Mei Qiao,
Yongping Zhang,
Yun Wu
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i6.875
Subject(s) - cell culture , biology , microbiology and biotechnology , stat3 , cell growth , electrophoretic mobility shift assay , cancer research , cell , signal transduction , vascular endothelial growth factor , gene expression , biochemistry , gene , vegf receptors , genetics
To investigate the difference in activation of STAT3 signaling between two human stomach adenocarcinoma cell lines: 5-fluorouracil resistant cell line and its parental cell line, and to evaluate its relationship with the expression of vascular endothelial growth factor (VEGF).