Open AccessYMDD mutations in patients with chronic hepatitis B untreated with antiviral medicines
Author(s) -
Zhong-Min Huang,
Qiwen Huang,
Yaqin Qin,
Yong He,
Houji Qin,
Yiao-Nan Zhou,
Xiang Xu,
Meijin Huang
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i6.867
Subject(s) - medicine , genotype , lamivudine , hepatitis b virus , virology , hbeag , nucleic acid , hepatitis b , incidence (geometry) , point mutation , chronic hepatitis , real time polymerase chain reaction , mutation , virus , gastroenterology , gene , biology , hbsag , genetics , physics , optics
To polymerase P region (YMDD) mutations of hepatitis B virus gene (HBV DNA) in patients with chronic hepatitis B (CHB) untreated with antiviral medicines and to explore its correlation with pre-c-zone mutations, HBV genotypes and HBV DNA level, and to observe its curative effect.