Open AccessCysteine peptidase and its inhibitor activity levels and vitamin E concentration in normal human serum and colorectal carcinomas
Author(s) -
Robert Szwed,
Zygmunt Grzebieniak,
Yousif Saleh,
Godwin Bwire Ekonjo,
Maciej Siewiński
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i6.850
Subject(s) - colorectal cancer , medicine , vitamin , cysteine , cysteine protease , gastroenterology , cancer , metastasis , endocrinology , enzyme , immunology , biology , biochemistry
Cysteine peptidase (CP) and its inhibitor (CPI) are a matrix protease that may be associated with colorectal carcinoma invasion and progression, and vitamin E is also a stimulator of the immunological system. Our purpose was to determine the correlation between the expression of cysteine peptidases and their endogenous inhibitors, and the level of vitamin E in sera of patients with colorectal cancer in comparison with healthy individuals.